digitoxin

Definitions:

  • A highly active glycoside, C<sub>41</sub>H<sub>64</sub>O<sub>13</sub>, derived from digitalis and prescribed in the treatment of certain cardiac conditions.
  • A poisonous principle obtained from <internalXref urlencoded="Digitalis">Digitalis</internalXref> in the form of yellowish crystals soluble in alcohol.
  • A steroid glycoside, one of the cardiotonic chemical substances which is extracted from the foxglove. It is a white, crystalline substance (C41H64O13), and is a 3-substituted triglucoside of a steroid, related structurally to digitalin and digoxin. It is used as a cardiotonic for treatment of certain heart conditions, such as congestive heart failure. Chemically it is (3β,5β)-3-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide. The related compounds <xref urlencoded="digitalin">digitalin</xref> and <xref urlencoded="digoxin">digoxin</xref> are also extracted from the foxglove (<spn>Digitalis lanata</spn> and <spn>Digitalis purpurea</spn>). The class of steroid glycosides having cardiotonic properties are refered to as the cardiac glycoside group.
  • A <xref>toxic</xref> <xref>cardiac</xref> <xref>glycoside</xref>, obtained from <xref>digitalis</xref>, related to <xref>cardenolide</xref>
  • digitalis preparation used to treat congestive heart failure or cardiac arrhythmia
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